Return to Newsletter Menu
A Symptom Overview - Current Treatments - Drugs in Development
Free & Low Cost Medication
a Good Doctor
Local Support Groups.
Filing for Disability
Medical Evaluation Form for Disability
FMS Community Newsletter. It's Free! Subscribe Today.
Fibrom-L. Online Support and
Open Letter To Normal's.
Manage Housework with Chronic Pain
Information for Children and Young Adults
|With summer in full swing, and heat
waves sweeping the U.S., I decided to use this issue of the editor's corner to share the
various ways people are beating the heat. These tips are from people that I know in
person, and those that I know via online support groups. They all have FM or CMP, CFIDS
and over lapping conditions.
Public Library You can go to any public library and sit and read, or use the internet,
even if you do not have a current library card. The majority of them allow you to bring in
snacks and drinks. Go to the library during the hottest part of the day, read a magazine,
surf the net or read a good book. Most of them offer comfy chairs, and most importantly,
Shop without money Even if you don't have money to spend, go to Wal-mart, k-mart or other
local stores and wander, or use the electric carts provided at the door. You can browse
the books, get decorating ideas or people watch as you cruise around. There is no law that
says you have to spend money when you go. Get out of the heat and take advantage of the
Hospitals Some folks go to their local hospital. Each hospital has multiple lobbies with
chairs, tv's and magazines. If they are desperate enough they go sit in the lobbies and
read, or watch TV.
Mall Get to a mall. By bus, or car pool. Cab or senior transport. They have air and you
can sit or walk all day and nobody cares. Many have electric carts you can borrow.
Freecycle Go to freecycle.com and sign up for your city. This is a site where people offer
items they don't want, but they don't want them to go into a landfill. You can often find
fans or air conditioners that people are giving away. You can post things you want to get
rid of and you may ask for items you "want" such as a fan. If someone has one
laying around, they will let you know and you can get it for free. *Tip: don't ask and ask
for things if you do not offer things. There is a code among freecyclers. You have to give
These are the tips I have gathered so far. If anyone has another great tip to share please
send it to firstname.lastname@example.org and we will get it to our
In This Issue:
~Fibromyalgia patients show an abnormal dopamine response to pain
~Australian researchers have identified a cluster of genes linked to chronic
~Intramuscular and nerve root stimulation vs lidocaine injection to trigger
points in myofascial pain syndrome
~Pharmacological treatment of fibromyalgia and other chronic musculoskeletal
~Cranial electrotherapy stimulation and fibromyalgia.
Fibromyalgia patients show an abnormal dopamine response to pain.
Eur J Neurosci. 2007 Jun;25(12):3576-82. Wood PB, Schweinhardt P, Jaeger E, Dagher A,
Hakyemez H, Rabiner EA, Bushnell MC, Chizh BA.
McGill University Centre for Research on Pain, Faculty of Dentistry, 3640 University
Street, Strathcona Building, Montreal, QC, Canada, H3A 2B2. PMID: 17610577
Fibromyalgia is characterized by chronic widespread pain and bodily tenderness and is
often accompanied by affective disturbances. Accumulating evidence indicates that
fibromyalgia may involve a dysfunction of modulatory systems in the brain.
While brain dopamine is best known for its role in pleasure, motivation and motor control,
recent evidence suggests that it is also involved in pain modulation. Because dopamine is
implicated in both pain modulation and affective processing, we hypothesized that
Fibromyalgia may involve a disturbance of dopaminergic
Fibromyalgia patients and matched healthy control subjects were subjected to deep muscle
pain produced by injection of hypertonic saline into the anterior tibialis muscle. In
order to determine the endogenous release of dopamine in response to painful stimulation,
used positron emission tomography to examine binding of [(11)C]-raclopride (D2/D3 ligand)
in the brain during injection of painful hypertonic saline and nonpainful normal saline.
Fibromyalgia patients experienced the hypertonic saline as more painful than healthy
control subjects. Control subjects released dopamine in the basal ganglia during the
painful stimulation, whereas fibromyalgia patients did not. In control subjects, the
amount of dopamine release correlated with the amount of perceived pain but in
fibromyalgia patients no such correlation was observed.
These findings provide the first direct evidence that fibromyalgia patients have an
abnormal dopamine response to pain. The disrupted dopaminergic reactivity in fibromyalgia
patients could be a critical factor underlying the widespread.
Australian researchers have identified a cluster of genes linked to
chronic fatigue syndrome
This mysterious illness finally be explained. The team from the University of NSW sifted
through more than six
million pieces of DNA information in people who had glandular fever, including half who
went on to develop chronic fatigue.
Their goal was to identify which genes appeared to be more active in the people who went
on to get fatigue, to shed light on what triggers the unexplained condition.
Professor Andrew Lloyd and his colleagues at the Centre for Infection and Inflammation
Research were able to find 35 genes linked to the symptoms of the illness. 'These (35)
genes might point to the nature
of the disease process that underlies chronic fatigue syndrome, which is currently
unknown,' said Prof Lloyd, whose findings are published in the latest Journal of
Chronic fatigue is most commonly triggered by an acute illness, like glandular fever. It
is characterised by extreme tiredness but recent studies have left researchers puzzled as
to what it actually is.
'We know it's not a psychiatric disorder, and doesn't appear to have anything to do with
immune responses or hormones or the severity of the virus,' Prof Lloyd said. 'So that's
left us thinking it's some kind of brain disorder.'
The team decided to analyse brain patterns by studying blood samples of 15 people with
glandular fever, including some who also developed fatigue. The work was part of a larger
project tracking the long-term
health of people infected by three infections - the mosquito borne Ross River virus, Q
fever bacterial infection and Epstein-Barr virus, which causes glandular fever - in the
central NSW city of Dubbo.
Prof Lloyd said the findings were the tentative beginnings of better understanding the
disease. 'It's given us the starting point for some gene expression pattern that might
become a diagnostic test for the condition,' he said. 'And it's given some clues of what
process might be that underlies the disorder. 2007 AAP
Intramuscular and nerve root stimulation vs lidocaine injection to
trigger points in myofascial pain syndrome
Journal of Rehabilitation Medicine. 2007 May;39(5):374-8. Authors and affiliation: Ga H,
Koh HJ, Choi JH, Kim CH. Department of Family Medicine, Inha University College of
Medicine, Incheon, Korea. PMID: 17549328
Objectives: To compare the efficacies of an intramuscular stimulation technique and 0.5%
lidocaine injection to trigger points in myofascial pain syndrome.
Participants: Forty-three people with myofascial pain syndrome of the upper trapezius
Interventions: Twenty-two subjects were treated with intramuscular stimulation and another
21 with 0.5% lidocaine injection at all the trigger points on days 0, 7 and 14.
Results: Intramuscular stimulation resulted in a significant reduction in Wong-Baker FACES
pain scale scores at all visits and was more effective than trigger point injection.
Intramuscular stimulation also resulted in significant improvement on the Geriatric
Depression Scale - Short Form. Local twitch responses occurred in 97.7% (42/43) of
patients. All the passive cervical ranges of motion were significantly increased.
Post-treatment soreness was noted in 54.6% of patients in the intramuscular stimulation
group and 38.1% in the trigger point injection group, respectively, and gross subcutaneous
haemorrhage (> 4 cm2) was seen in only one patient in the trigger point injection
Conclusion: In managing myofascial pain syndrome, after one month intramuscular
stimulation resulted in more significant improvements in pain intensity, cervical range of
motion and depression scales than did 0.5% lidocaine injection of trigger points.
Intramuscular stimulation is therefore recommended for myofascial pain syndrome.
Pharmacological treatment of fibromyalgia and other chronic
Best Pract Res Clin Rheumatol. 2007 Jun;21(3):499-511. Goldenberg DL. Newton-Wellesley
Hospital, Division of Rheumatology, 2000 Washington Street, Suite 304, Newton, MA 02468,
USA. Best Pract Res Clin Rheumatol. 2007 Jun;21(3):499-511. PMID: 17602996
The pharmacologic management of fibromyalgia is based on the emerging evidence that pain
in this disorder is primarily related to central pain sensitization.
There is strong evidence that tricyclic antidepressants are effective, and moderate
evidence for the effectiveness of serotonin reuptake inhibitors and dual
serotonin-norepinephrine reuptake inhibitors.
Recent work suggests that the anti-seizure medications pregabalin and gabepentin are also
The only analgesic demonstrated to be helpful is tramadol.
Cranial electrotherapy stimulation and fibromyalgia.
Expert Rev Med Devices. 2007 Jul;4(4):489-95. Gilula MF. President and Director, Life
Energies Research Institute, 2510 Inagua Avenue, Miami, FL 33133, USA. email@example.com. PMID: 17605684
Cranial electrotherapy stimulation (CES) is a well-documented neuroelectrical modality
that has been proven effective in some good studies of fibromyalgia (FM) patients. CES is
no panacea but, for some FM patients, the modality can be valuable.
This article discusses aspects of both CES and FM and how they relate to the individual
with the condition. FM frequently has many comorbidities such as anxiety, depression,
insomnia and a great variety of different rheumatologic and neurological symptoms that
often resemble multiple sclerosis, dysautonomias, chronic fatigue syndrome and others.
However, despite long-standing criteria from the American College of Rheumatology for FM,
some physicians believe there is probably no single homogeneous condition that can be
labeled as FM.
Whether it is a disease, a syndrome or something else, sufferers feel like they are living
one disaster after another. Active self-involvement in care usually enhances the
therapeutic results of various treatments and also improves the patient's sense of being
in control of the condition. D-ribose supplementation may prove to
significantly enhance energy, sleep, mental clarity, pain control and well-being in FM
patients. A form of evoked potential biofeedback, the EPFX
[Electro-Physio-Feedback-Xrroid], is a powerful stress reduction technique which assesses
the chief stressors and risk
factors for illness that can impede the FM patient's built-in healing abilities.
Future healthcare will likely expand the diagnostic criteria of FM and/or illuminate a
group of related conditions and the ways in which the conditions relate to each other.
Future medicine for FM and related conditions may increasingly involve multimodality
treatment that features CES as one significant part of the therapeutic regimen.
Future medicine may also include CES as an invaluable, cost-effective add-on to many
facets of clinical pharmacology and medical therapeutics.